BackgroundMobile phone SMS text message reminders have shown moderate effects in improving participation rates in ongoing colorectal cancer screening programs. ObjectiveThis study aimed to assess the effectiveness of SMS text messages as a replacement for routine postal reminders in a fe...

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Main Authors: Nuria Vives, Gemma Binefa, Noemie Travier, Albert Farre, Jon Aritz Panera, Berta Casas, Carmen Vidal, Gemma Ibáñez-Sanz, Montse Garcia
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Acesso em linha:https://doaj.org/article/aec4a64be0b0465a86043b84395b3f6e
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author Nuria Vives
Gemma Binefa
Noemie Travier
Albert Farre
Jon Aritz Panera
Berta Casas
Carmen Vidal
Gemma Ibáñez-Sanz
Montse Garcia
author_facet Nuria Vives
Gemma Binefa
Noemie Travier
Albert Farre
Jon Aritz Panera
Berta Casas
Carmen Vidal
Gemma Ibáñez-Sanz
Montse Garcia
date_str_mv 2025-01-01T00:00:00Z
description BackgroundMobile phone SMS text message reminders have shown moderate effects in improving participation rates in ongoing colorectal cancer screening programs. ObjectiveThis study aimed to assess the effectiveness of SMS text messages as a replacement for routine postal reminders in a fecal immunochemical test–based colorectal cancer screening program in Catalonia, Spain. MethodsWe conducted a randomized controlled trial among individuals aged 50 to 69 years who were invited to screening but had not completed their fecal immunochemical test within 6 weeks. The intervention group (n=12,167) received an SMS text message reminder, while the control group (n=12,221) followed the standard procedure of receiving a reminder letter. The primary outcome was participation within 18 weeks of the invitation. The trial was stopped early, and a recovery strategy was implemented for nonparticipants in the intervention group. We performed a final analysis to evaluate the impact of the recovery strategy on the main outcome of the trial. Participation was assessed using a logistic regression model adjusting for potential confounders (sex, age, and deprivation score index) globally and by screening behavior. ResultsThe trial was discontinued early in September 2022 due to the results of the interim analysis. The interim analysis included 5570 individuals who had completed 18 weeks of follow-up (intention-to-treat). The SMS text message group had a participation rate of 17.2% (477/2781), whereas the control group had a participation rate of 21.9% (610/2789; odds ratio 0.71, 95% CI 0.62-0.82; P<.001). As a recovery strategy, 7591 (72.7%) out of 10,442 nonparticipants in the SMS text message group had an open screening episode and received a second reminder by letter, reaching a participation rate of 23% (1748/7591). The final analysis (N=24,388) showed a participation rate of 29.3% (3561/12,167) in the intervention group, which received 2 reminders, while the participation rate was 26.5% (3235/12,221) in the control group (odds ratio 1.16, 95% CI 1.09-1.23; P<.001). ConclusionsReplacing SMS text messages with reminder letters did not increase the participation rate but also led to a decline in participation among nonparticipants 6 weeks after the invitation. However, sending a second reminder by letter significantly increased participation rates among nonparticipants within 6 weeks in the SMS text message group compared with those who received 1 postal reminder (control group). Additional research is essential to determine the best timing and frequency of reminders to boost participation without being intrusive in their choice of participation. Trial RegistrationClinicalTrials.gov NCT04343950; https://www.clinicaltrials.gov/study/NCT04343950
doi_str 10.2196/64243
format Article
id oai_oai_doaj.org_article_aec4a64be0b0465a86043b84395b3f6e
issn_str_mv 2291-5222
language_str_mv EN
oai_datestamp_str 2025-01-01T16:15:27Z
oai_identifier_str oai:doaj.org/article:aec4a64be0b0465a86043b84395b3f6e
publisher_str JMIR Publications
relation_str_mv https://mhealth.jmir.org/2025/1/e64243
https://doaj.org/toc/2291-5222
source_str JOURNAL_A
source_txt JMIR mHealth and uHealth, Vol 13, p e64243 (2025)
spellingShingle Text Messaging Versus Postal Reminders to Improve Participation in a Colorectal Cancer Screening Program: Randomized Controlled Trial
Nuria Vives
Gemma Binefa
Noemie Travier
Albert Farre
Jon Aritz Panera
Berta Casas
Carmen Vidal
Gemma Ibáñez-Sanz
Montse Garcia
subject_str_mv Information technology
T58.5-58.64
Public aspects of medicine
RA1-1270
title Text Messaging Versus Postal Reminders to Improve Participation in a Colorectal Cancer Screening Program: Randomized Controlled Trial
type_str article
url https://doaj.org/article/aec4a64be0b0465a86043b84395b3f6e